On the first desktop, let's say you want to have only your home notes.
1. First you will have to hide all the existing desktop notes from Notezilla notes menu.
2. Then go to the memoboard where you have home notes. Select all notes (Ctrl+A) and then choose 'Stick to desktop' option as shown below:
3. Later when you are back to work, you can go back to the same option and choose 'Remove from desktop'.
And then show all your work notes back on the desktop notes that were earlier hidden, by following the same steps again for the work notes.
Watch this short video that depicts this: